姓名：刘承伟

出生年月：1987.11

办公室：上海大学宝山校区E514

实验室：上海大学宝山校区HA514

职称：教授

职务：博士生导师、硕士生导师

地址：上海市宝山区上大路99号

邮箱：liuchengwei@shu.edu.cn; liuchengwei2024@163.com

课题组网站：https://www.x-mol.com/groups/chengwei_liu

个人简介

刘承伟，2020年于美国罗格斯新泽西州立大学取得博士学位，师从Michal Szostak教授。2020年至2021年在英国牛津大学Stephen P. Fletcher课题组，开展博士后研究工作。2021年9月至2022年6月在南京信息工程大学工作。2022年6月加入上海大学，开展教学科研工作。先后在新型扭曲酰胺的发现与应用、酰胺的交叉偶联、羧酸的脱羰偶联等领域做出了多项原创性工作，在Angew. Chem. Int. Ed.、ACS Catalysis等期刊上发表高水平学术论文四十余篇。由于研究工作的创新性和重要性，他获得了国际贵金属协会颁发的“2020 International Precious Metals Institute Student Award”、中国国家留学基金委颁发的“2019国家优秀自费留学生奖学金”、美国罗格斯新泽西州立大学颁发的“2021 Outstanding Dissertation Award”和“2019 Dissertation Fellowship”。目前主持上海市海外高层次人才引进项目一项。

课题组研究方向

稀土金属有机、二价稀土金属诱导的自由基反应、过渡金属催化。

招生情况

课题组常年招收化学及相关专业研究生，欢迎积极联系。

同时欢迎本科生来实验室开展本科毕业设计。

开展独立研究工作后取得的成果

2024

35. Li, K.; Li, R.; Cui, Y.;* Liu, C.* Decarbonylative Borylation of Aryl Anhydrides via Rhodium Catalysis, Org. Biomol. Chem. 2024, 22, doi: 10.1039/d3ob01949g.

34. Chen, L.; Ji, H.; Ding, Y.;* Szostak, M.;* Liu, C.* Palladium-Catalyzed Decarbonylative Sonogashira Alkynylation of Carboxylic–Phosphoric Anhydrides, J. Org. Chem. 2024, 89, doi: 10.1021/acs.joc.3c02701.

2023

33. Zhang, W.; Ma, J.; Zhou, F.; Szostak, M.;* Liu, C.* Carboxylic Acids as Double Aryl Group Donors for Biaryl Synthesis, Org. Chem. Front. 2023, 10, 5698-5704.

32. Ji, H.; Cao, H.; Wang, G.; Xing, F.;* Szostak, M.;* Liu, C.* Predominant Intermolecular Decarbonylative Thioetherification of Carboxylic Acids using Nickel Precatalysts, Org. Chem. Front. 2023, 10, 4275-4281.

31. Bie, F.; Liu, X.*; Szostak, M.*; Liu, C.* Decarbonylative Alkynylation of Aryl Anhydrides via Palladium Catalysis, J. Org. Chem. 2023, 88, 4442-4451.

30. Liu, C.*; Szostak, M.* Amide N–C Bond Activation: A Graphical Overview of Acyl and Decarbonylative Coupling, SynOpen 2023, 7, 88-101.

29. Liu, C.*; Xing, Y. Y.; Zhou, T.; Chen, T.*; Hong, X.*; Szostak, M.* Carboxylic–Phosphoric Anhydrides as Direct Electrophiles for Decarbonylative Hirao Cross-Coupling of Carboxylic Acids: DFT Investigation of Mechanistic Pathway, Chem Asian J. 2023, 18, e202201262.

28. Shi, Y.; Ji, C.-L.*; Liu, C.* “Palladium-Catalyzed Difunctionalization of Norbornenes via Arylation and Alkynylation” J. Org. Chem. 2023, 88, 261-271.

2022

27. Liu, C.*; Szostak, M.* “Decarbonylative Sonogashira Cross-Coupling: Fruitful Marriage of Alkynes with Carboxylic Acid Electrophiles” Org. Chem. Front. 2022, 9, 216-222.

2021

26. Liu, C.*; Szostak, M.* “Forging C–S Bonds Through Decarbonylation: New Perspectives for the Synthesis of Privileged Aryl Sulfides” ChemCatChem 2021, 13, 4878-4881.

25. Zhang, W.; Bie, F.; Ma, J.; Zhou, F.; Szostak, M.*; Liu, C.* “Palladium-Catalyzed Decarbonylative Borylation of Aryl Anhydrides” J. Org. Chem. 2021, 86, 17445-17452.

24. Bie, F.; Liu, X.; Cao, H.; Shi, Y.; Zhou, T.; Szostak, M.*; Liu, C.* “Pd-Catalyzed Double-Decarbonylative Aryl Sulfide Synthesis through Aryl Exchange between Amides and Thioesters” Org. Lett. 2021, 23, 8098-8103.

23. Cao, H.; Liu, X.; Bie, F.; Shi, Y.; Han, Y.; Yan, P.; Szostak, M.*; Liu, C.* “Rh(I)-Catalyzed Intramolecular Decarbonylation of Thioesters” J. Org. Chem. 2021, 86, 10829-10837.

22. Shi, Y.; Liu, X.; Cao, H.; Bie, F.; Yan, P.; Han, Y.; Szostak, R.; Szostak, M.*; Liu, C.* “Conversion of Esters to Thioesters via C–O Bond Cleavage/Weak C–S Bond Formation under Transition-Metal-Free Conditions” Org. Biomol. Chem. 2021, 19, 2991-2996.

21. Cao, H.; Liu, X.; Bie, F.; Shi, Y.; Han, Y.; Yan, P.; Szostak, M.*; Liu, C.* “General and Practical Intramolecular Decarbonylative Coupling of Thioesters via Palladium Catalysis” Org. Chem. Front. 2021, 8, 1587-1592.

2020

20. Bie, F.; Liu, X.; Shi, Y.; Cao, H.; Han, Y.; Szostak, M.*; Liu, C.* “Rh-Catalyzed Base-Free Decarbonylative Borylation of Twisted Amides” J. Org. Chem. 2020, 85, 15676-15685.

读博期间取得的成果(2015-2020)

19. Liu, C.*; Szostak, M.* “Decarbonylative Sulfide Synthesis from Carboxylic Acids and Thioesters via Cross-Over C–S Activation and Acyl Capture” Org. Chem. Front. 2021, 8, 4805-4813.

18. Liu, C.; Szostak, M.* “Decarbonylative Sonogashira Cross-Coupling of Carboxylic Acids” Org. Lett. 2021, 23, 4726-4730.

17. Liu, C.; Ji, C.-L.; Zhou, T.; Hong, X.*; Szostak, M.* “Bimetallic Cooperative Catalysis for Decarbonylative Heteroarylation of Carboxylic Acids via C–O/C–H Coupling” Angew. Chem. Int. Ed. 2021, 60, 10690-10699.

16. Liu, C.; R.; Lalancette, R.; Szostak, R.; Szostak, M. “Sterically Hindered Ketones via Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling of Amides by N–C(O) Activation” Org. Lett. 2019, 21, 7976-7981.

15. Liu, C.; Ji, C.-L.; Qin, Z.-X.; Hong, X.; Szostak, M. “Synthesis of Biaryls via Decarbonylative Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling of Carboxylic Acids” iScience 2019, 19, 749-759.

14. Liu, C.; Qin, Z.-X.; Ji, C.-L.; Hong, X.; Szostak, M. “Highly-Chemoselective Step-Down Reduction of Carboxylic Acids to Aromatic Hydrocarbons via Palladium Catalysis” Chem. Sci. 2019, 10, 5736-5742.

13. Liu, C.; Shi, S.; Liu, Y.; Liu, R.; Lalancette, R.; Szostak, R.; Szostak, M. “The Most Twisted Acyclic Amides: Structures and Reactivity” Org. Lett. 2018, 20, 7771-7774.

12. Liu, C.; Ji, C.-L.; Hong, X.; Szostak, M. “Palladium-Catalyzed Decarbonylative Borylation of Carboxylic Acids: Tuning Reaction Selectivity by Computation” Angew. Chem. Int. Ed. 2018, 57, 16721-16726.

11. Liu, C.; Li, G.; Shi, S.; Meng, G.; Lalancette, R.; Szostak, R.; Szostak, M. “Acyl and Decarbonylative Suzuki Coupling of N-Acetyl Amides: Electronic Tuning of Twisted, Acyclic Amides in Catalytic Carbon–Nitrogen Bond Cleavage” ACS Catal. 2018, 8, 9131-9139.

10. Liu, C.; Szostak, M. “Decarbonylative Cross-Coupling of Amides” Org. Biomol. Chem. 2018, 16, 7998-8010.

9. Liu, C.; Szostak, M. “Decarbonylative Thioetherification by Nickel Catalysis Using Air- and Moisture-Stable Nickel Precatalysts” Chem. Commun. 2018, 54, 2130-2133.

8. Liu, C.; Szostak, M. “Decarbonylative Phosphorylation of Amides by Palladium and Nickel Catalysis: The Hirao Cross-coupling of Amide Derivatives” Angew. Chem. Int. Ed. 2017, 56, 12718-12722.

7. Liu, C.; Liu, Y.; Liu, R.; Lalancette, R.; Szostak, R.; Szostak, M. “Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling of N-Mesylamides by N–C Cleavage: Electronic Effect of the Mesyl Group” Org. Lett. 2017, 19, 1434-1437.

6. Liu, C.; Szostak, M. “Twisted Amides: From Obscurity to Broadly Useful Transition-Metal- Catalyzed Reactions by N–C Amide Bond Activation” Chem. Eur. J. 2017, 23, 7157-7173.

5. Liu, C.; Meng, G.; Szostak, M. “N-Acylsaccharins as Amide-Based Arylating Reagents via Chemoselective N–C Cleavage: Pd-Catalyzed Decarbonylative Heck Reaction” J. Org. Chem. 2016, 81, 12023-12030.

4. Liu, C.; Meng, G.; Liu, Y.; Liu, R.; Lalancette, R.; Szostak, R.; Szostak, M. “N-Acylsaccharins: Stable Electrophilic Amide-Based Acyl Transfer Reagents in Pd-Catalyzed Suzuki-Miyaura Coupling via N–C Cleavage” Org. Lett. 2016, 18, 4194-4197.

3. Liu, C.; Achtenhagen, M.; Szostak, M. “Chemoselective Ketone Synthesis by the Addition of Organometallics to N-Acylazetidines” Org. Lett. 2016, 18, 2375-2378.

读硕士期间取得的成果(2011-2014)

2. Liu, C.; Zhang, Y.; Qian, Q.; Yuan, D.; Yao, Y. “n-BuLi as a Highly Efficient Precatalyst for Hydrophosphonylation of Aldehydes and Unactivated Ketones” Org. Lett. 2014, 16, 6172-6175.

1. Liu, C.; Qian, Q.; Nie, K.; Wang, Y.; Shen, Q.; Yuan, D.; Yao, Y. “Lanthanide Anilido Complexes: Synthesis, Characterization, and Use as Highly Efficient Catalysts for Hydrophosphonylation of Aldehydes and Unactivated Ketones” Dalton Trans. 2014, 43, 8355- 8362.

以共同作者身份发表的成果

7. Li, H.; Hou, Y.; Liu, C.; Lai, Z.; Ning, L.; Szostak, R.; Szostak, M.*; An, J.* Pentafluorophenyl Esters: Highly Chemoselective Ketyl Precursors for the Synthesis of α,α-Dideuterio Alcohols Using SmI2 and D2O as a Deuterium Source, Org. Lett. 2020, 22, 1249-1253.

6. Wang, C.-A.; Liu, C.; Szostak, M.* N-Acyl-5,5-Dimethylhydantoins: Mild Acyl-Transfer Reagents for the Synthesis of Ketones Using Pd-PEPPSI or Pd/Phosphine Catalysts, Org. Process Res. Dev. 2020, 24, 1043-1051.

5. Rahman, M. M.; Liu, C.; Bisz, E.; Dziuk, B.; Lalancette, R.; Wang, Q.; Chen, H.; Szostak, R.; Szostak, M.* N-Acyl-glutarimides: Effect of Glutarimide Ring on the Structures of Fully Perpendicular Twisted Amides and N−C Bond Cross-Coupling, J. Org. Chem. 2020, 85, 5475-5485.

4. Szostak, R.; Liu, C.; Lalancette, R.; Szostak, M.* Twisted N-Acyl-hydantoins: Rotationally Inverted Urea-Imides of Relevance in N−C(O) Cross-coupling, J. Org. Chem. 2018, 83, 14676-14682.

3. Osumi, Y.; Liu, C.; Szostak, M.* N-Acylsuccinimides: Twist-Controlled, Acyl-transfer Reagents in Suzuki-Miyaura Cross-Coupling by N−C Amide Bond Activation, Org. Biomol. Chem. 2017, 15, 8867-8871.

2. Nie, K.*; Liu, C.; Zhang, Y.; Yao, Y.* Syntheses of Bimetallic Rare-Earth Bis(cyclopentadienyl) Derivatives Supported by Bridged Bis(guanidinate) Ligands and Their Catalytic Property for the Hydrophosphonylation of Aldehydes, J. Organomet. Chem. 2016, 804, 59-65.

1. Nie, K.*; Liu, C.; Zhang, Y.; Yao, Y.* Syntheses of Bimetallic Lanthanide Bis(amido) Complexes Stabilized by Bridged Bis(guanidinate) Ligands, Sci. China Chem. 2015, 58, 1451-1460.