崔雷,博士,硕士生导师,上海大学理学院副教授。2006年9月进入于华东理工大学药物化工研究所攻读博士学位,师从钱旭红院士和徐玉芳教授。目前已在Angew. Chem, Nature. Comm, Chem.Comm等期刊上发表文章35篇,其文章他引次数超过1100次。目前主要从事精细化学品的设计及工艺开发,聚焦于电子级化学,特殊用于光芯片,光通讯领域的光学树脂及粘合剂的开发工作。目前部分产品已经成功应用有华为海思的芯片及光学模组领域。
在研项目:
1. 光学染料的构效关系研究及开发,企业项目,2021年3月-2023年2月,120万
2. 镜头模组用高折树脂的研究与开发,企业项目,2019年11月-2022年10月,100万
3. 显隐材料的开发,企业项目,2020年05月-2022年04月,20万
部分发表论文:
(1) Fei, Y.; Hu, J.; Wang, Z.; Cui, L.; Jia, X.; Li, C.; Li, J. Exploring the Reactivity of Propargylic Ester: Acyloxy and Acyl Migratory Rearrangement Relay Enabled by Formal Double Isocyanide Insertion. Advanced Synthesis & Catalysis 2021.
(2) Xu, K.; Zhang, Z. Y.; Yu, C.; Wang, B.; Dong, M.; Zeng, X.; Gou, R.; Cui, L.; Li, C. A modular synthetic strategy for functional macrocycles. Angewandte Chemie International Edition 2020, 59 (18), 7214.
(3) Wang, Y.; Yang, L.-P.; Zhao, X.; Cui, L.; Li, J.; Jia, X.; Fang, J.; Li, C. Multiple Stimuli-Responsive Conformational Exchanges of Biphen [3] arene Macrocycle. Molecules 2020, 25 (24), 5780.
(4) Liu, X.; Gu, F.; Zhou, X.; Zhou, W.; Zhang, S.; Cui, L.; Guo, T. A naphthalimide-based turn-on fluorescence probe for peroxynitrite detection and imaging in living cells. RSC Advances 2020, 10 (63), 38281.
(5) Li, B.; Xu, K.; Wang, Y.; Su, H.; Cui, L.; Li, C. Selective complexation and efficient separation of cis/trans-1, 2-dichloroethene isomers by a pillar [5] arene. RSC Advances 2020, 10 (73), 45112.
(6) Li, B.; Cui, L.; Li, C. Macrocycle Co‐Crystals Showing Vapochromism to Haloalkanes. Angewandte Chemie International Edition 2020, 59 (49), 22012.
(7) Huang, J.; Li, F.; Cui, L.; Su, S.; Jia, X.; Li, J. Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application. Chemical Communications 2020, 56 (33), 4555.
(8) Yuan, H.; Tang, C.; Su, S.; Cui, L.; Jia, X.; Li, C.; Li, J. A bicyclization reaction with two molecular allenyl ketones and isocyanides: synthesis of a lactone-containing azaspirocycle derivative. Chemical Communications 2019, 55 (50), 7231.
(9) Wang, Y.; Xu, K.; Li, B.; Cui, L.; Li, J.; Jia, X.; Zhao, H.; Fang, J.; Li, C. Efficient Separation of cis‐and trans‐1, 2‐Dichloroethene Isomers by Adaptive Biphen [3] arene Crystals. Angewandte Chemie 2019, 131 (30), 10387.
(10) Wang, C.; Zhang, S.; Huang, J.; Cui, L.; Hu, J.; Tan, S. Novel designed azo substituted semi-cyanine fluorescent probe for cytochrome P450 reductase detection and hypoxia imaging in cancer cells. RSC advances 2019, 9 (37), 21572.
(11) Li, B.; Wang, B.; Huang, X.; Dai, L.; Cui, L.; Li, J.; Jia, X.; Li, C. Terphen [n] arenes and Quaterphen [n] arenes (n= 3–6): One‐Pot Synthesis, Self‐Assembly into Supramolecular Gels, and Iodine Capture. Angewandte Chemie International Edition 2019, 58 (12), 3885.
(12) Chen, J.; Ni, H.; Meng, Z.; Wang, J.; Huang, X.; Dong, Y.; Sun, C.; Zhang, Y.; Cui, L.; Li, J. Supramolecular trap for catching polyamines in cells as an anti-tumor strategy. Nature communications 2019, 10 (1), 1.
(13) Zeng, X.; Deng, H.; Jia, X.; Cui, L.; Li, J.; Li, C.; Fang, J. Construction of [2] rotaxane-based supramolecular polymers driven by wheel-stopper π⋯ π interactions. Chemical Communications 2018, 54 (82), 11634.
(14) Huang, X.; Zhang, X.; Qian, T.; Ma, J.; Cui, L.; Li, C. Synthesis of a water-soluble 2, 2′-biphen [4] arene and its efficient complexation and sensitive fluorescence enhancement towards palmatine and berberine. Beilstein journal of organic chemistry 2018, 14 (1), 2236.
(15) Bao, L.; Shu, X.; Yu, M.; Hou, D.; Cui, L.; Li, C. Synthesis, structure, and host-guest properties of an anthracene-based macrocyclic arene. Tetrahedron Letters 2018, 59 (8), 730.
(16) Ping, G.; Wang, Y.; Shen, L.; Wang, Y.; Hu, X.; Chen, J.; Hu, B.; Cui, L.; Meng, Q.; Li, C. Highly efficient complexation of sanguinarine alkaloid by carboxylatopillar [6] arene: p K a shift, increased solubility and enhanced antibacterial activity. Chemical Communications 2017, 53 (53), 7381.
(17) Li, Z.; Qu, S.; Cui, L.; Zhang, S. Detection of carbofuran pesticide in seawater by using an enzyme biosensor. Journal of Coastal Research 2017, (80), 1.
(18) Kwon, N.; Cho, M. K.; Park, S. J.; Kim, D.; Nam, S.-J.; Cui, L.; Kim, H. M.; Yoon, J. An efficient two-photon fluorescent probe for human NAD (P) H: quinone oxidoreductase (hNQO1) detection and imaging in tumor cells. Chemical Communications 2017, 53 (3), 525.
(19) Dai, L.; Ding, Z.-J.; Cui, L.; Li, J.; Jia, X.; Li, C. 2, 2′-Biphen [n] arenes (n= 4–8): one-step, high-yield synthesis, and host–guest properties. Chemical Communications 2017, 53 (89), 12096.
(20) Cui, L.; Shi, Y.; Zhang, S.; Yan, L.; Zhang, H.; Tian, Z.; Gu, Y.; Guo, T.; Huang, J. A NIR turn-on fluorescent probe applied in cytochrome P450 reductase detection and hypoxia imaging in tumor cells. Dyes and Pigments 2017, 139, 587.