课题组简介： 本课题组（元素有机与催化研究室，Laboratory of Elementary Organic Chemistry and Catalysis，LEOC）成立于2022年3月，隶属于上海大学理学院化学系。本课题组拟开展元素有机和催化方向的研究工作，包括有氟化合物，有机硅化合物的合成，将重点关注具有功能性的含氟、含硅化合物的高效、高选择性合成。开发的催化方式包括均相催化，非均相催化，光催化等等。 目前课题组有充足的科研经费，常年招收科研助理，硕士生，博士生以及博士后（上海大学博士后泮池计划），欢迎有志青年的加入。 教育经历： 2012.09 - 2017.07 北京大学 化学与分子工程学院 有机化学 博士（导师：张艳 教授，王剑波 教授） 2008.09 - 2012.07 兰州大学 化学化工学院 化学基地班 学士（导师1：王为 教授；导师2：翟宏斌 教授） 工作经历： 2022.03 - 至 今 上海大学，教授 2017.10 - 2021.12 瑞士洛桑联邦理工学院（EPFL） 基础科学院 博士后（导师：Xile Hu教授） 代表性科研项目： 1.2022 上海市海外高层次人才计划（青年拔尖项目） 2.2023 国家自然科学基金（青年项目） 3.2023 国家海外高层次人才项目 代表性学术论文： 独立后：敬请期待。。。 独立前： 1. Z. Zhang, X. Hu, "Visible-Light-Driven Catalytic Deracemization of Secondary Alcohols", Angew. Chem. Int. Ed. 2021, 61, 22833-22838. 2. Z. Zhang, # B. Srikrishna,# C. Fan, X. Hu, "Streamlined Alkylation via Nickel-Hydride-Catalyzed Hydrocarbonation of Alkenes", J. Am. Chem. Soc. 2022, 144, 7015-7029. (Perspective, # co-first author) 3. Z. Zhang, X. Hu, "Arylsilylation of Electron-Deficient Alkenes via Cooperative Photoredox and Nickel Catalysis", ACS Catal. 2020, 10, 777−782. 4. Z. Zhang, L. Bai, X. Hu, "Alkene Hydrosilylation Catalyzed by Easily Assembled Ni(II)-Carboxylate MOFs", Chem. Sci. 2019, 10, 3791-3795. 5. R. Zhang,# Z. Zhang,# Q. Zhou, L. Yu, J. Wang, " Generation of Difluoroketenimine and Its Application in the Synthesis of α, α-Difluoro-β-amino Amides" Angew. Chem. Int. Ed. 2019, 58, 5744-5748. (# co-first author) 6. Z. Zhang, Z. Sheng, W. Yu, G. Wu, R. Zhang, W. Chu, Y. Zhang, J. Wang, "Asymmetric Trifluoromethylthiolation via Enantioselective [2,3]-Sigmatropic Rearrangement of Sulfonium Ylide Generated from Metal Carbene and Sulfide", Nat. Chem. 2017, 9, 970-976. 7. Z. Zhang, W. Yu, C. Wu, C. Wang, Y. Zhang, J. Wang, "Reaction of Diazo Compounds with Difluorocarbene: An Efficient Approach toward 1,1-Difluoroolefins", Angew. Chem. Int. Ed. 2016, 55, 273-277. 8. Z. Zhang, Q. Zhou, W. Yu, T. Li, Y. Zhang, J. Wang, "Cu(I)-Catalyzed Three-Component Coupling of Trifluoromethyl Ketone N-Tosylhydrazones, Alkynes and Azides: Synthesis of Difluoromethylene Substituted 1,2,3-Triazoles", Chin. J. Chem. 2017, 35, 387-391. 9. Z. Zhang, W. Yu, Q. Zhou, T. Li, Y. Zhang, J. Wang, "Rh(I)-Catalyzed Reaction of Trifluoromethylketone N-Tosylhydrazones and Arylboronates", Chin. J. Chem. 2016, 34, 473-476. 10. Z. Zhang, Q. Zhou, W. Yu, T. Li, G. Wu, Y. Zhang, J. Wang, "Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes", Org. Lett. 2015, 17, 2474-2477. 11. Z. Zhang, Q. Zhou, F. Ye, Y. Xia, G. Wu, M. L. Hossain, Y. Zhang, J. Wang, "Cu(I)-Catalyzed Three Component Coupling of N-Tosylhydrozones, Alkynes and Azides: Synthesis of Trisubstituted 1,2,3-Triazoles", Adv. Synth. Cat. 2015, 357, 2277-2286. 12. Z. Zhang, J. Feng, Y. Xu, S. Zhang, Y. Ye, T. Li, X. Wang, J. Chen, Y. Zhang, J. Wang, "Synthesis of Trifluoromethylated Cycloheptatrienes from N-Tosylhydrazones: Transition-Metal-Free Büchner Ring Expansion", Synlett, 2015, 26, 59-62. 13. R. Zhang, Z. Zhang, K. Wang, J. Wang, Difluoroketenimine: Generation from Difluorocarbene and Isocyanide and Its [3 + 2] Cycloadditions with Alkenes or Alkynes, J. Org. Chem. 2020, 85, 15, 9791–9800. 14. R. Shi, Z. Zhang, X. Hu, "Nickamine and Analogous Nickel Pincer Catalysts for Cross Coupling of Alkyl Halides and Hydrosilylation of Alkenes" Acc. Chem. Res. 2019, 52, 1471-1483. 15 Z. Sheng, M. Ma, L. Peng, Z. Zhang, C. Chu, Y. Zhang, J. Wang, "Cu(I)-Catalyzed Stereoselective Doyle-Kirmse Reaction", Chin. J. Org. Chem. 2017, 37, 1730-1740. 16. Q. Zhou, Z. Zhang, Y. Zhou, S. Li, Y. Zhang, J. Wang, "Palladium-Catalyzed Synthesis of Indoles and Isoquinolines with in-situ Generated Phosphinimine" J. Org. Chem. 2017, 82, 48-56. 17. Z. Sheng, Z. Zhang, C. Chu, Y. Zhang, J. Wang, "Transition Metal-Catalyzed [2, 3]-Sigmatropic Rearrangements of Ylides: An Update of the Most Recent Advances", Tetrahedron 2017, 73, 4011-4022. (Invited review article) 18. W.-D. Chu, L. Zhang, Z. Zhang, Q. Zhou, F. Mo, Y. Zhang, J. Wang, "Enantioselective Synthesis of Trisubstituted Allenes via Cu(I)-Catalyzed Coupling of Diazoalkanes with Terminal Alkynes", J. Am. Chem. Soc. 2016, 138, 14558-14561. 19. C. Wu, Z. Liu, Z. Zhang, F. Ye, G. Deng, Y. Zhang, J. Wang, “Cu(I)-Catalyzed Stereoselective Synthesis of (E)-α-Alkynyl-α, β-unsaturated Esters from Terminal Alkyne, Diazoesters and Aldehydes”, Adv. Synth. Cat. 2016, 358, 2480-2488. 20. H. Li, Z. Zhang, X. Shangguan, S. Huang, J. Chen, Y. Zhang, J. Wang, “Pd(0)-Catalyzed Cross Coupling of 1,1-Diboronates with Vinyl Bromides and 1,1-Dibromoalkenes”, Angew. Chem. Int. Ed. 2014, 53, 11921-11925. 21. H. Li, X. Shangguan, Z. Zhang, S. Huang, Y. Zhang, J. Wang, “Formal Carbon Insertion of N-Tosylhydrazone into B-B and B-Si Bonds: gem-Diborylation and gem-Silylborylation of sp3 Carbon”, Org. Lett. 2014, 16, 448-451. 22. C. Wang, Z. Zhang, T. Yue, Y. Sun, L. Wang, W. D. Wang, Y. Zhang, C. Liu, W. Wang, “Bottom-Up Embedding of the Jørgensen–Hayashi Catalyst into a Chiral Porous Polymer for Highly Efficient Heterogeneous Asymmetric Organocatalysis”, Chem. Eur. J. 2012, 18, 6718-6723. (Cover paper) |