【个人简历】 2002/09-2006/07: 同济大学，理学院，学士 2008/08-2013/08: 美国奥本大学，理学院，博士 2013/10-2014/12：美国BioLegend生物技术公司，产品开发科学家 2015/01-2018/05：美国俄亥俄州立大学，博士后，导师：Prof. Ly James Lee 2018/07-2023/05：华南师范大学，研究员、博士生导师 2023/06-至今：上海大学，教授、博士生导师 【研究方向】 纳米生物传感与核酸/蛋白分子诊断 CRISPR-Cas系统与疾病诊疗 水体污染物检测与治理 【人才项目】 国家海外高层次人才引进计划青年项目（重点资助） 广东省“珠江人才计划” 【科研项目】 (1)国家科技部重点研发计划，2023.11-2026.10，主持 (2)基于CRISPR系统便携式即时诊断技术研发（横向），2024.02-2026.10，主持 (3)广州市重点研发计划，2022.04-2025.03，主持 (4)宁波市“科技创新2025”重大专项，2020.10-2023.09，主持 (5)国家自然科学基金青年科学基金项目，2019.01-2021.12，主持 (6)国家自然科学基金应急管理项目，2018.01-2018.12，主持 (7)广东省自然科学基金面上项目，2022.01-2025.12，主持 【论文著作】：第一作者或通讯作者文章(按时间倒序排列) (1)Hongrui Zhao#, Yan Sheng#*, Tenghua Zhang, Shujun Zhou, Yuqing Zhu, Feiyang Qian, Meiru Liu, Weixue Xu, Dengsong Zhang*, Jiaming Hu*, The CRISPR-Cas13a Gemini System for noncontiguous target RNA activation. Nature Communications 2024, 15 (1), 2901. (2)Yuqing Zhu, Jianming Zhou, Yuxin Liang, Yao Lu, Shujun Zhou, Feiyang Qian, Tenghua Zhang, Yan Sheng*, Jiaming Hu*, Cas-Rainbow: Cas12a-driven single-reaction multiplex detection system. Chemical Engineering Journal 2024, 480, 148212. (3)Tenghua Zhang#, Zihui Xie#, Xiaohe Zheng#, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng*, Jiaming Hu*, CRISPR-Cas12a powered hybrid nanoparticle for extracellular vesicle aggregation and in-situ microRNA detection. Biosensors and Bioelectronics 2024, 245, 115856. (4)Bowen Jiang, Tenghua Zhang, Silan Liu, Yan Sheng*, Jiaming Hu*, Polydopamine-assisted aptamer-carrying tetrahedral DNA microelectrode sensor for ultrasensitive electrochemical detection of exosomes. Journal of Nanobiotechnology 2024, 22 (1), 55. (5)Yuqing Zhu#, Xiaohe Zheng#, Rui Zhu, Hongrui Zhao, Hongli Zhai, Feiyang Qian, Tenghua Zhang, Zihui Xie, Silan Liu, Bowen Jiang, Yan Sheng*, Jiaming Hu*, CRISPR-Cas12a powered multifunctional DNA nanodumbbell lock biosensor for multiple molecular detection. Chemical Engineering Journal 2023, 468, 143494. (6)Yan Sheng#, Zena Huang#, Tenghua Zhang#, Feiyang Qian, Yuqing Zhu, Zaizai Dong, Qingyang Zhang, Qi Lei, Fanhui Kong, Yuqiong Wang, Maddie Walden, Stefan Wuttke, Lingqian Chang*, Wei Zhu*, Jiaming Hu*, Living Cell Nanoporation and Exosomal RNA Analysis Platform for Real-Time Assessment of Cellular Therapies. Journal of the American Chemical Society 2022, 144 (21), 9443-9450. (7)Feiyang Qian#, Zena Huang#, Hankang Zhong, Qi Lei, Yiru Ai, Zihui Xie, Tenghua Zhang, Bowen Jiang, Wei Zhu*, Yan Sheng*, Jiaming Hu*, C. Jeffrey Brinker, Analysis and Biomedical Applications of Functional Cargo in Extracellular Vesicles. ACS Nano 2022, 16 (12), 19980-20001. (8)Yan Sheng#, Tenghua Zhang#, Shihong Zhang#, Midori Johnston, Xiaohe Zheng, Yuanyue Shan, Tong Liu, Zena Huang, Feiyang Qian, Zihui Xie, Yiru Ai, Hankang Zhong, Tairong Kuang*, Can Dincer*, Gerald Anton Urban, Jiaming Hu*, A CRISPR/Cas13a-powered catalytic electrochemical biosensor for successive and highly sensitive RNA diagnostics. Biosensors and Bioelectronics 2021, 178, 113027. (9)Jinjin Shen, Xiaoming Zhou, Yuanyue Shan, Huahua Yue, Ru Huang, Jiaming Hu*, Da Xing*, Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction. Nature Communications 2020, 11 (1), 267. (10)Jiaming Hu*, Kwang Joo Kwak, Junfeng Shi, Bohao Yu, Yan Sheng*, Ly James Lee*, Overhang molecular beacons encapsulated in tethered cationic lipoplex nanoparticles for detection of single-point mutation in extracellular vesicle-associated RNAs. Biomaterials 2018, 183, 20-29. (11)Jiaming Hu*, Tairong Kuang*, DNA-Coded Fluorescence for Color Painting RNAs. Chem 2018, 4 (6), 1194-1196. (12)Jiaming Hu#*, Yan Sheng#*, Kwang Joo Kwak, Junfeng Shi, Bohao Yu, L. James Lee*, A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection. Nature Communications 2017, 8 (1), 1683. (13)Lingqian Chang#, Jiaming Hu#, Feng Chen, Zhou Chen, Junfeng Shi, Zhaogang Yang, Yiwen Li*, Ly James Lee*, Nanoscale bio-platforms for living cell interrogation: current status and future perspectives. Nanoscale 2016, 8 (6), 3181-3206. (14)Jiaming Hu, Yajiao Yu, Jessica C. Brooks, Leah A. Godwin, Subramaniam Somasundaram, Ferdous Torabinejad, Joonyul Kim, Curtis Shannon*, Christopher J. Easley*, A Reusable Electrochemical Proximity Assay for Highly Selective, Real-Time Protein Quantitation in Biological Matrices. Journal of the American Chemical Society 2014, 136 (23), 8467-8474. (15)Jiaming Hu#, Tanyu Wang#, Joonyul Kim, Curtis Shannon, Christopher J. Easley, Quantitation of Femtomolar Protein Levels via Direct Readout with the Electrochemical Proximity Assay. Journal of the American Chemical Society 2012, 134 (16), 7066-7072. |