【个人简历】 1996/9-2000/7 中国石油大学（华东），化学化工学院，学士 2001/9-2006/3 浙江大学，化学系，博士（导师：张永敏教授） 2006/3-2009/3 上海大学，理学院化学系，讲师 2009/3-2014/3 上海大学，理学院化学系，副教授 2012/10-2013/10 瑞士洛桑联邦理工学院，化学科学与工程学院，访问学者(导师:Jieping Zhu教授) 2014/3- 至今 上海大学，理学院化学系，教授 【研究方向】 1.有机合成方法学 2.基于异腈的串联反应 3.药物类似分子与医药中间体的合成修饰 【科研项目】 1. 炔丙醇酯芳基异腈构建多环骨架体系的设计、合成及应用研究 国家自然科学基金面上项目，2024年1月至2027年12月，主持 2. 基于不饱和亚胺中间体的多组分反应策略构建多样性含氮杂环研究 上海市科学技术委员会自然科学基金，面上项目，2021年8月至2024年6月，主持 3. 基于官能化异腈的三组分反应构建复杂多环骨架的研究 上海市科学技术委员会自然科学基金，面上项目，2018年6月至2021年5月，主持 4. 水参与下基于异腈的四组分串联加成/环化反应研究 国家自然科学基金面上项目，2013年1月至2016年12月，主持 5. 异腈引发联烯酸酯参与的多组分环加成反应研究 国家自然科学基金青年科学基金项目，2011年1月至2013年12月，主持 6. 用于薄膜的光学染料包裹技术开发及工艺生产 横向项目，2022年9月至2024年8月，主持 7. 巨豆三烯酮中试合成工艺研究 横向项目，2021年12月至2023年8月，主持 8. 基于新型骨架结构的手性磷酸结构合成及修饰 横向项目，2021年3月2023年3月，主持 【论文著作】 (1) Shen, J.; Xing, Y.; Fu, L.; Li, Y.; Cui, L.; Zhou, Z.;* Li, C.; Li, J.* Sequential [3+2] and [4+4] Annulation of Diynone and o-Hydroxyaryl Azomethine Ylide: Construction of Dihydropyrrole Fused Eight-Membered Ring Scaffold, Advanced Synthesis & Catalysis, 2023, 365, 4175-4180. (2) Chen，H.; Lin, L.; Meng, Y.; Li, J.;* Huang, S.;* Hong, R.* All-in-One Synthesis of 3,6-Dideoxysugars: An Olefin Metathesis–Isomerization Approach, Organic Letters, 2023, 25, 6429-6433. (3) Li, S.; Zhang, Z.-Y.; Lv, J.-F.; Li, L.; Li, J.; Li, C.* Macrocyclization-Induced Phosphorescence Enhancement of Pyridinium-based Macrocycle Journal of Material Chemistry A, 2023, 11, 4957-4962. (4) Xiao, Y.; Peng, X.; Shen, J.; Cui, L.; Lu, S.; Jia, X.; Li, C.; Li, J.* Cascade reaction of o-enoyl arylisocyanide and o-hydroxy aromatic aldimine: diastereoselective access to a polycyclic spirobenzoxazine chromeno[4,3-b]pyrrole derivative, Chemical Communications, 2022, 58, 10528-10531. (5) Shen, J.; Xiao, Y.; Zhao, P.; Li, D.; Jia, X.; Peng, X.; Li, J.* Cascade Reaction of o-Haloaryl Ynone and 2-Hydroxy-2-Methylchromene: Synthesis of Chromone Derivative Enabled by Oxygen-Migration Advanced Synthesis & Catalysis, 2022, 364, 291-295. (6) Zhao, L.; Chen, J.; Tian, L.; Zhang, Y.; Chen, L.; Du, X.; Ma, M.; Li, J.; Meng, Q.;* Li, C.* Supramolecular Detoxification of Macromolecular Biotoxin through the Complexation by a Large-Sized Macrocycle Advanced Healthcare Materials,2022, 11,2200270. (7) Wang, Z.; Fei, Y.; Tang, C.; Cui, L.; Shen, J.; Yin, K.; Lu, S.; Li, J.* Diastereoselective Synthesis of Tetracyclic Tetrahydroquinoline Derivative Enabled by Multicomponent Reaction of Isocyanide, Allenoate, and 2-Aminochalcone Organic Letters, 2021, 23, 4094-4098. (8) Huang, J.; Li, F.; Cui, L.; Su, S.; Jia, X.; Li, J.* Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application Chemical Communications, 2020, 56, 4555-4558. (9) Wang, Y.; Zhang, Y.; Zhou, Z.; Vanderlinden, R. T.; Li, B.; Song, B.; Li, X.; Cui, L.; Li, J.; Jia, X.; Fang, J.; Li, C.* Peter J. Stang A cyclic bis[2]catenane metallacage Nature Communications, 2020, 11, 2727-2735. (10) Xue, B.; Su, S.; Cui, Y.; Fei, Y.; Jia, X.; Li, J.,* Fang, J. Phosphine-mediated sequential annulations of allenyl ketone and isocyanide: a bicyclization trategy to access a furan-fused eight-membered ring and a spirocycle Chemical Communications, 2019, 55, 12180-12183. (11) Yuan, H.; Tang, C.; Su, S.; Cui, L.; Jia, X.; Li, C.; Li, J.* A bicyclization reaction with two molecular alenyl ketones and isocyanides: synthesis of a lactone-containing azaspirocycle derivative Chemical Communications, 2019, 55, 7231-1234. (12) Yuan, H.; Liu, Z.; Shen, Y.; Zhao, H.; Li, C.; Jia, X.; Li, J.* Iron-Catalyzed Oxidative Coupling Reaction of Isocyanides and Simple Alkanes towards Amide Synthesis Advanced Synthesis & Catalysis, 2019, 361, 2009-2013. (13) Hu, J.; Fei, Y.; Zhao, H.; Wang, Z.; Li, C.; Li, J.* Cascade cyclization and acyl migration of propargylic esters with isocyanides: rapid access to substituted furans, Chemical Communications, 2019, 55, 8394-8397. (14) Chen, J.; Ni, H.; Meng, Z.; Wang, J.; Huang, X.; Dong, Y.; Sun, C.; Zhang, Y.; Cui, L.; Li, J.; Jia, X.; Meng, Q.; Li, C.* Supramolecular trap for catching polyamines in cells as an anti-tumor strategy Nature Communications. 2019,10, 3546. (15) Li, B.; Wang, B.; Huang, X.; Dai, L.; Cui, L.; Li, J.; Jia, X.; Li, C.* Terphen[n]arenes and Quaterphen[n]arenes (n=3-6): One-Pot Synthesis, Self-Assembly into Supramolecular Gels, and Iodine Capture, Angewandte Chemie-Intermational Edition, 2019, 58, 3885-3889. (16) Su, S.; Hu, J.; Cui, Y.; Tang, C.; Chen, Y.;* Li, J.* A formal (5+1) annulation reaction from heterodimerization of two different isocyanides: stereoselective synthesis of 2H-benzo[b][1,4]oxazin-2-one, Chemical Communications, 2019, 55, 12243-12246. (17) Li, F.; Hu, P.; Sun, M. M.; Li, C. J.; Jia, X. S.,* Li, J.* Ytterbium and silver co-catalyzed synthesis of pyrrole-fused bicyclic skeletons from enynones and isocyanides Chemical Communications, 2018, 54, 6412-6415. (18) Li, J. X.; Chen, Y. Y.; Yuan, H. D.; Hu, J.; Cui, Y. M.; Yang, M.; Li, M., Li, J.* Phosphine‐Catalyzed Domino Reaction of α,β‐Unsaturated Ketone and Allenoate: Stereoselective Synthesis of Polysubstituted Dihydro‐2H‐Pyran Advanced Synthesis & Catalysis, 2018, 360, 2333-2338. (19) Zhang, X.; Liu, Z.; Gao, Y.; Hu, J.; Tian, Y.; Li, C. J.; Jia, X. S.; Li, J.* Selective Oxidative Coupling Reaction of Isocyanides Using Peroxide as Switchable Alkylating and Alkoxylating Reagent Advanced Synthesis & Catalysis, 2018, 360, 272-277. (20) Jin, T.; Tang, Z. Z.; Hu, J.; Yuan, H.; Li, C. J.; Jia, X. S.; Li, J.* Iron-Catalyzed Aerobic Oxidation and Annulation Reaction of Pyridine and α-Substituted Allenoate toward Functionalized Indolizine Organic Letters, 2018, 20, 412-416. (21) Li, B.; Meng, Z.; Li, Q.; Huang, X.; Kang, Z.; Dong, H.; Chen, J.; Sun, J.; Li, J.; Jia, X.; Sessler, J. L.;* Meng, Q.; Li, C. J.* A pH responsive complexation-based drug delivery system for oxaliplatin Chemical Science, 2017, 8, 4458-4464. (22) Liu, Z.; Zhang, X.; Li, J. X.; Li, F.; Li, C. J.;, Jia, X. S., Li, J.* Exploiting the Reactivity of Isocyanide: Coupling Reaction between Isocyanide and Toluene Derivatives Using the Isocyano Group as an N1 Synthon，Organic Letters，2016，18, 4052-4055. (23) Tian, Y.; Tian, L.; Li, C. J.; Jia, X. S.;* Li, J.* Temperature-Dependent Double Isocyanide Insertion Reaction To Construct a Polycyclic Skeleton，Organic Letters，2016，18, 840-843. (24) Li, C. L.; Jin, T.; Zhang, X. L.; Li, C. J.; Jia, X. S.;* Li, J.*Bu4NI-Catalyzed alpha-Oxyacylation of Carbonyl Compounds with Toluene Derivatives，Organic Letters，2016，18, 1916-1919. |