【教育及工作经历】

2015/09-2020/06    上海有机化学研究所 博士 导师：沈其龙 研究员

2020/07-2021/10    上海有机化学研究所 助理研究员 导师：沈其龙/吕龙 研究员

2021/11-2023/06     宾夕法尼亚大学 博士后 导师 Gary. A. Molander

2023/07-至 今          上海大学 教授

【研究方向】

本课题组致力于发展新颖的有机方法学，实现对具有高附加值的有机小分子特别是含氟小分子高效、简洁合成

研究手段包括可见光催化、过渡金属催化和不对称催化

此外，我们致力于探究反应机制，以深入了解反应，为开发新的催化体系提供理论基础

欢迎对光催化和过渡金属催化感兴趣的本科生和研究生加入课题组

【人才项目】

上海市海外高层次人才计划（青年拔尖）

【科研项目】

上海市海外高层次人才引进项目 2023.9-2026.9 主持

【论文著作】

1. A General and Practical Route to Functionalized BCPs Enabled by Photocatalytic Multicomponent Heteroarylation of [1.1.1]Propellane” Huang, W. C.; Keess, Sebastian.; Molander, G. A. Angew. Chem. Int. Ed. 2023, 62, e2023022.

2. A General and Modular Approach to BCP Alkylamines via Multicomponent Difunctionalization of [1.1.1]Propellane” Huang, W. C†.; Zheng, Y. X†.; Keess, Sebastian.; Molander, G. A. J. Am. Chem. Soc. 2023, 145, 5363-5369

3. Dicarbofunctionalization of [1.1.1]Propellane Enabled by Nickel/Photoredox Dual Catalysis: One-Step Multicomponent Strategy for the Synthesis of BCP-Aryl Derivatives” Huang, W. C.; Keess, Sebastian.; Molander, G. A. J. Am. Chem. Soc. 2022, 144, 12961-12969.

4. Facilitating the Transmetalation step with Aryzincates in Nickel-Catalyzed Enantioselective Arylation of Secondary Bezylic Halides” Huang, W. C.; Hu, M.; Wan, X. L.; Shen, Q Nat. Commun. 2019, 10, 2963.

5. Enantioselective Construction of Trifluoromethoxylated stereogenic Centers by a Nickel-Catalyzed Asymmetric Suzuki-Miyaura Coupling of secondary Benzylic Bromides” Huang, W. C.; Wan. X. L.; Shen, Q Angew. Chem. Int. Ed. 2017, 56, 11986.

6. Photochemical Intermolecular [3σ + 2σ]-Cycloaddition for the Construction of Aminobicyclo[3.1.1]heptanes. Zheng, Y. X†.; Huang, W. C†.; Dhungana, R. K.; Granados, A.; Keess, Sebastian.; Makvandi, M.; Molander, G. A. J. Am. Chem. Soc. 2022, 144, 23685-23690. (†co-first author)

7. One Step Synthesis of Unsymmetrical 1,3- Disubstituted BCP Ketones via Nickel/Photoredox-Catalyzed [1.1.1]Propellane Multicomponent Dicarbofunctionalization. Huang, W. C.; Keess, S.; Molander, G. A. Chem. Sci. 2022, 13, 11936-11942.

8. Cobalt-Catalyzed Asymmetric Cross-Coupling Reaction of Fluorinated Secondary Benzyl Bromides with Lithium Aryl 3 Boronates/ZnBr₂ Huang, W. C.; Wan. X. L.; Shen, Q. Org. Lett. 2020, 22, 11, 4327.

9. Stereoselective Formation of Z-Monofluoroalkenes by Nickel-catalyzed Defluorinative Coupling of Gem‑Difluoroalkenes with Lithium Organoborates” Xiao, Y, S†.; Huang, W. C†.; Shen, Q. Chin. Chem. Lett. 2022, 33, 4277.

10. Diimidazolium Salt HBDIM: An Easily Available, Low-Cost CageCarbene Precursor with Broad Applications in Transition Metal-Catalyzed Reactions Jiang, W. K.; Huang, W. C†.; Xu, M. C.; Shen, Q. Chem. Eur. J. 2023, 29, e2023009. (†co-first author)